The study is first of its kind to notice the differences between males and females for the marijuana affects.
The study conducted on male and female rats found that female rats are 30 percent more responsive to Tetrahydrocannabinol (THC). THC is the psychoactive constituent in the cannabis plant.
Rebecca Craft the professor of Pathology from Washington State University said that the tolerance shown by female rats is more compared to the male rats. This means is a possibility that females are more prone for the side effects of Marijuana than men.
Dr Craft said the tetrahydrocannabinol sensitivity among females was at peak when females are ovulating indicating that estrogen levels place an important role in this case.
Dr Craft explained, “What we’re finding with THC is that you get a very clear spike in drug sensitivity right when the females are ovulating – right when their estrogen levels have peaked and are coming down.”
The study was published in the journal Drug and Alcohol Dependence.