A recent study by the researchers at the University Of Cambridge, UK defies the verdicts of past research that clinches that higher concentrations of circulating vitamin D might avoid type 2 diabetes.
“Our findings suggest that interventions to reduce the risk of type 2 diabetes by increasing concentrations of vitamin D are not currently justified,” said Nita Forouhi at the Medical Research Council (MRC) Epidemiology Unit at the University Of Cambridge School Of Clinical Medicine.
“Our findings are in agreement with the results of randomised controlled trials, which provide a classic way to assess cause-effect relationships, and which have generally shown that type 2 diabetes was not prevented in individuals taking vitamin D supplements.”
The researchers discovered no genetic substantiation of vitamin D levels controlling the risk of emerging type 2 diabetes.
The results were published Sept. 30 in The Lancet Diabetes & Endocrinology journal.
Dr Forouhi and colleagues also inspected the association of vitamin D status and type 2 diabetes’ functional characteristics like glucose and glycated haemoglobin. The researchers established no confirmation of a causal link.
Dr Forouhi suggested that the observational studies indicating a strong and regular greater risk of type 2 diabetes with lesser intensities of vitamin D might be due to the fact that they are not successful in effectively controlling factors like the level of physical activity that may be connected with both vitamin D levels and the risk of type 2 diabetes.
However, “we are far from done with this topic,” says Dr. Forouhi who advocates further clinical trials and observational studies to find out more accurate connection between the factors that might link vitamin D to disease.
In an accompanying commentary in the journal he results, Dr Brian Buijsse, from the German Institute of Human Nutrition Potsdam-Rehbruecke, Germany, wrote, The study, “need careful interpretation, and long-term randomized trials of vitamin D supplementation, which are underway, remain important.”
“The results of an [analysis] of 35 short-term trials, however, do not offer much hope that vitamin D supplementation can be used to prevent type 2 diabetes. The sky is becoming rather clouded for vitamin D in the context of preventing type 2 diabetes,” added Buijsse.